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Frank (Duplass) and Zoe (Wilde) are engaged, but their wedding has been delayed by their research into a serum that can reanimate the deceased. After having success bringing back to life a dead dog, they discover that the university is shutting down their work — and that a mysterious corporation will be seizing their intellectual property. Defying their bosses, Frank and Zoe and the rest of their team (Donald Glover, Evan Peters and Sarah Bolger) decide to do one more experiment, which leaves Zoe dead from an accidental electrocution. Not willing to let her go, Frank decides to use the serum on his fiancée, with disastrous results.